Regime questions

Heya,
I am self medicating myself as I have no support of my parents and the doctors here won't do it without their support until age 21 (19 atm).

I have started on Estrofem, Spiro and Duphaston and I am looking to change my formula.

Would like suggestions.
Dutas 0.5mg per day, generic dutasteride.
Estrofem 6mg per day.
Siterone (generic Androcur): 50mg per day (is it enough or should I aim for 100mg?)
Duphaston: 10mg once in two days (should I take it every day?), considering to change to Microgest 200mg per day (also unsure of the dosage).

Thanks in advance!

You seem to be taking an awful lot of overlapping drugs. I am quite concerned about your dosing.

If you are taking Androcur, you don't need Microgest. Both are progesterones. One of my doctors considers Androcur to be a superior form of progesterone.

You don't need to be taking dutasteride and cyproterone (androcur) at the same time. Both have similar effects (just two different ways of going about it). Both these drugs are heavy duty. DON'T underestimate the potential side effects. Taking both is putting a lot of strain on your body and it's ability to process these drugs. The estrogen is already doing this on it's own

Unless you have an already visible balding problem, I would drop the dutasteride.
The estrogen and androcur will do the job just fine. If you do have a balding problem, drop the androcur and just take dutasteride although because of your age, any apparent balding would probably be reversible with estrogen and androcur alone.

I would also recommend you take a combination of ethinyl estradiol and estradiol. I take 100mcg/day of ethinyl estradiol and 10mg/week of estradiol valerate injection. This is a common pre-op dosing regime. Alternatively, 50mcg/day ethinyl estradiol and a higher dosage of estradiol.

Also, try and make your second estrogen transdermal. Transdermal estrogen puts a lot less strain on the body and bypasses the liver. Most doctors now use transdermal estrogen on post-op or older transsexuals for this reason - less complications. Sandrena gel, estradiol injections or patches are commonly available.

I would take a low dose of aspirin to counter the blood clotting affects of estrogen. (approx 100-200mg/day).

Remember that these drugs can dramatically alter your body chemistry. You need to have regular blood tests to check you are not damaging your body. You can die from some of these drugs by damaging your liver. You only have one so look after it.

You need to monitor your liver function, kidney function and prolactin levels along with your testosterone and estrogen levels regularly. Find a doctor who is sympathetic.

Heya,
Sorry for slow response to you, been busy lately.
I just wanted to state that I am not yet taking those medicines (I am taking 6mg estrofem and 200mg spiro per day for now and wanting to change).

Where I am, there is no person treating transgenders in about 100km radius, so I have to do it myself.

If you'd to suggest a whole new regimen, what would it be, including dosage? knowing I can't have injection though.

One with patch and one without patch in case I can't get it.

Thanks

I take:

• 100mcg ethinyl estradiol/day
• 10mg estradiol valerate/week
• 100mg spironolactone/day
• 200mg Aspiring/day

I am thinking of lowering the ethinyl estradiol to 50mcg/day and increasing the estradiol valerate to 20mg/week.

I wouldn't be taking duasteride/finasteride unless I had a balding problem. If you do have a balding problem then you really need to do some research as both cyproterone and duasteride are heavy duty drugs and may have interactions. I think both drugs were originally used to treat cancer which should give you an idea of how powerful they are.

Also, cyproterone is a progesterone so you don't need to take progesterone in addition to cyproterone. Some doctors wont prescribe progesterone for transsexuals for various reasons including mental instability and little perceived benefit. Some clinics prescribe progesterone for only the first 6 months of hormone treatment (to assist breast growth), but you could simply use this instead of spironolactone. I don't because it is expensive here and I don't have a body or facial hair problem.

I have my kidney and liver function checked regularly. If you have impaired liver or kidney function, a high hormone dosage could potentially kill you or cause you serious concern. You need to work out how you can monitor your kidney and liver function. These are not uncommon so maybe you could ask your doctor for a general check up and casually mention kidney and liver function tests. Blood clotting would be handy to know also.

I am sure if you searched hard enough you would find a doctor willing to help regardless of regulations. Perhaps a GLBT or sexual health clinic? You could try telling a doctor you are self medicating regardless of what anyone says and you just need blood tests to check your health.

Good luck and be careful.

M.

Anything to lower DHT or have you passed surgery yet? (seeing as you're taking low levels of spiro)

Thanks for the help

DHT is produced by the prostate and as far as I am aware, the prostate isn't removed during srs. Therefore, surgical status isn't that important. More important is your testosterone levels. DHT is produced by the prostate converting normal testosterone. If you have low testosterone which should happen as a result of estrogen, spiro or cyproterone then your body wont produce much testosterone and therefore DHT. It is important to note that a small amount of testosterone is important for overall health in women. The human brain produces small amounts of testosterone naturally even in females. Having absolutely no testosterone is not desirable. This is why I suggested that unless you have a balding problem (DHT causes balding more than normal testosterone) then I wouldn't bother with a 5alpha reductase inhibitor - cyproterone should work perfectly well. That is only my personal opinion though.

Hey again!
Um, I am finally able to make an order, I am thinking of

100mcg ethinyl estradiol/day
50mg cyproterone/day

and I am looking into your suggestion of 10mg estradiol valerate/week
Can you please tell me of a certain medicine name? so far I have found of Progynon Depot but not sure if that's what you meant.

Another one I found is Progynova, any comments on that one?

progynova is good. it's a pill product, if i'm not mistaken?
some kind of estrogen. i've taken it and had good effect. imo of course.

Ok, thanks.

So

100mcg ethinyl estradiol/day
50mg cyproterone(siterone)/day
10mg progynova/week

How does it sound for a regime?

hi i need your help guys..my hair in my body and in my face is really depressing me..especially my mustache that makes me look obvious like a transgender..i have some premarin 0.25mg and spironolactone 50mg and 100mg..do you think these can help to lessen the hair on my body especially on my face too?and can i take two(2) 0.25premarin in a day with spironolactone?
and i heard the DEPO PROVERA is a nice hormone to reduce hair on body?please help me with this i would really appreciate it..thank you so much GOD BLESS